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AMI5 inhibitor br Introduction Gas hydrates are crystalline
2020-08-06

Introduction Gas hydrates are crystalline solid compounds in which gas molecules (called guest molecules) are surrounded by water molecules, forming a regular cavity crystalline structure. Gas molecules with a desirable shape and size such as methane, ethane, propane, carbon dioxide and etc. can
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Also our data from this study
2020-08-05

Also, our data from this study indicate that gestational GC exposure altered hematological and hemorheological parameters, however reports exist that altered blood rheological markers are associated with atherosclerosis and CVD (Tzoulaki et al., 2007). Also, the platelet to lymphocyte ratio (PLR) ha
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br Introduction Type Diabetes mellitus T DM is
2020-08-05

Introduction Type 2 Diabetes mellitus (T2DM) is a metabolic disorder that raises blood glucose level for a prolonged time. T2DM is associated with acute complications like ketoacidosis, hyposmolar coma, chronic complications include heart disease, stroke, kidney failure, foot ulcers and damage to
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br Tumors with other CREB family transcription factor fusion
2020-08-05

Tumors with other CREB family transcription factor fusions Summary The EWSR1 gene is notable for its ability to rearrange with a wide variety of fusion partners to generate an array of distinct, mostly mesenchymal tumors that show a variety of morphologic features and clinical behaviors. It is
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The Ewing s sarcoma family tumor ESFT is the
2020-08-05

The Ewing\'s sarcoma family tumor (ESFT) is the second most common bone malignancy after osteosarcoma [13]. ESFT includes Ewing sarcoma of bone, extra-osseous Ewing sarcoma (ES), primitive neuroectodermal tumor (PNET) and Askin\'s tumors [14]. ES is a disease affecting children and young adults with
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br Results and discussion br
2020-08-04

Results and discussion Materials and methods Acknowledgements S. Ślusarczyk received support from Polish National Center of Science postdoctoral grant FUGA (2014/12/S/NZ9/00715) under the appreciated mentoring of Prof. Dr. Anna Stochmal from IUNG Institute of Cultivation and Soil Science at
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In the present study we focused on the role
2020-08-04

In the present study, we focused on the role of ET-1 in SAH and our data indicated that the BQ-123 administered intracisternally increases the microcirculatory blood flow in the rabbit model of SAH and results in Etoricoxib tissue protection as demonstrated in the histological findings. Our results
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The cytoplasmic domain of classical cadherins is
2020-08-04

The cytoplasmic domain of classical cadherins is highly conserved and can interact with different cytosolic proteins. Typically this domain is associated with catenin family members, including p120 catenin, β-catenin, and α-catenin, which form a cadherin-catenin complex (Fig. 1). The catenin family
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DeFazio et al have used
2020-08-04

DeFazio et al. (2002) have used a brilliant combination of biochemical and EM experiments to visualise a synaptic complex. Synapsis takes place where the two broken DNA ends are brought together to facilitate ligation of their backbones, to restore genomic integrity. Several repair factors must cont
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As shown in a previous
2020-08-03

As shown in a previous report (Donatti and Leite-Panissi, 2011), microinjection of CRF into the BLA or CeA of the guinea pig increased the duration of TI episodes compared to control episodes (Fig. 2A–D). However, when the microinjection of CRF into the BLA or CeA was preceded by the injection of CP
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The survival of patients with aspergillosis is highly depend
2020-08-03

The survival of patients with aspergillosis is highly dependent on the ability to make an early and accurate diagnosis. Since the isolation of organisms is rarely successful, this study was designed to determine the GM index and loteprednol etabonate Ct values to evaluate the cut-off values for pos
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br Conclusion br Acknowledgments The authors acknowledge
2020-08-03

Conclusion Acknowledgments The authors acknowledge support from NSF grant 1445344. Introduction The worldwide emergence of Klebsiella pneumoniae carbapenemase (KPC)-producing Enterobacteriaceae poses a great challenge to healthcare [1]. Expression of KPC-type β-lactamases confers decreased
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s3i Introduction Ewing sarcomas primitive neuroectodermal tu
2020-08-03

Introduction Ewing sarcomas/primitive neuroectodermal tumors (ES/PNETs) are relatively infrequent but the second most common sarcoma of the bone next to osteosarcoma. Nearly 80% of them occur in persons younger than 20years. Most of them arise from the bone, but 10 to 20% of them from soft tissue.
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br Materials and Methods br Results br Discussion The abilit
2020-08-03

Materials and Methods Results Discussion The ability of pathogens to modulate the host fibrinolytic system is a crucial characteristic for tissue invasion. Plasminogen is an abundant protein of the host fibrinolytic system which upon activation into plasmin dissolves fibrin clots [12]. Eith
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We next focused our design building into the
2020-08-03

We next focused our design building into the ribose binding site, which had not been yet utilized in this effort. Compounds bearing a series of five-membered aromatic heterocycles (compound , ) showed reduced inhibition of the Gram-positive isozymes compared with compound , but a 20-fold improved po
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