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br Introduction Cherry tomato Solanum lycopersicum L is a co
2022-05-04

Introduction Cherry tomato (Solanum lycopersicum L.) is a commonly consumed fruit on a worldwide scale due to its characteristic flavor and high nutrition (Wei et al., 2016, Yu et al., 2014). Tomato is low in fat and calories, and is a rich natural source of nutrition and bioactive antioxidant co
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Assuming thus a positive signal for
2022-05-04

Assuming thus a positive signal for both GLUT1 and GLUT3 in our conditions, a more detailed explanation of the results observed through immunocytochemistry is needed. In this way, it must be reminded that syncytiotrophoblasts compose the outer layer of the trophoblast, are in direct contact with mat
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In mammals a major physiological role
2022-05-04

In mammals, a major physiological role of the GHSR gene appears to be in regulating food intake and energy homeostasis by partaking in the neuronal mechanisms involving neuropeptide Y and agouti-related protein (Nakazato et al., 2001, Chen et al., 2017). In our study, determination of the abundance
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In conclusion a novel series of
2022-05-04

In conclusion, a novel series of GPR40 agonists containing nitrogen heterocyclic rings derived from TAK-875 were designed and synthesized. The structural activity relationship studies indicated that the substituents on the nitrogen FR 180204 had a remarkable effect on the GPR40 agonistic activity.
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In enzyme assays it is
2022-04-29

In enzyme assays, it is convenient to quantify the product formed in the enzyme reaction, where a decrease in the concentration of product indicates enzyme inhibition [35], [36], [37], [38]. In the present study, substrates were carefully chosen so that they are specific to each enzyme. Known natura
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br Role of catecholamines in HIV associated neuroinflammatio
2022-04-29

Role of catecholamines in HIV-associated neuroinflammation Concluding remarks However, more research is needed to determine the precise mechanisms responsible for the immunomodulatory effects of catecholamines, including the involvement of specific receptors and signaling pathways in immune ce
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br Histamine attenuates the cognitive impairing effects of e
2022-04-29

Histamine attenuates the cognitive impairing effects of early postnatal maternal deprivation Histamine acting on H2 receptors in the hippocampal CA1 region is able to reverse the deleterious effect of the exposure of rats to partial postnatal maternal deprivation on their memory consolidation of
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br STAR Methods br Acknowledgments We
2022-04-29

STAR★Methods Acknowledgments We thank the TCGA PanCanAtlas Analysis Working Group. This study was supported in part by grants from the NIH (CA175486 and CA209851 to H.L., CA217842 to G.B.M., and CCSG grant CA016672); a grant from the Cancer Prevention and Research Institute of Texas (RP140462
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Under normal physiological conditions the body has
2022-04-29

Under normal physiological conditions, the body has sufficient oxygen supply, so glucose can produce large amounts of ATP by aerobic oxidation and oxidative phosphorylation in cells. After SCI, hypoxia ischemia can occur in local tissue, leading to decreasing of intracellular oxygen partial pressure
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gpr40 agonist br Introduction Glycolysis plays a
2022-04-29

Introduction Glycolysis plays a key role in gpr40 agonist energy metabolism [[1], [2], [3]]. It is initiated mainly by hexokinase I (HKI), the major hexokinase isoform of the brain ([3,4] and references therein). Up to 90% of brain HKI is bound to the mitochondrial outer membrane (MOM) through t
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The observed tendency for higher plasma lactate levels in
2022-04-29

The observed tendency for higher plasma lactate levels in the aerated thermal exposure suggests increased reliance on ApexPrep DNA Plasmid Miniprep Column Only metabolism to maintain function. This finding is supported by a recent study that observed an increased ṀO2 in European perch (Perca fluviat
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In conclusion studies of the regulation of the HO
2022-04-29

In conclusion, studies of the regulation of the HO-1/BVR/CO pathway by selective pharmacological approaches may lead to the discovery of novel compounds for the treatment of diverse diseases. Recent results validate the use of advances in targeting HO-1 in various vascular diseases. However, there
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Hh signaling pathway plays an essential role in the regulati
2022-04-29

Hh signaling pathway plays an essential role in the regulation of invertebrate and vertebrate tissue development and metabolic homeostasis. Components of Hh signaling pathway have been identified in succession, including Hh ligands, membrane protein receptors, cytoplasmic components and transcriptio
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Aspartame l aspartyl l phenylalanine methylester is a dipept
2022-04-29

Aspartame (l-aspartyl l-phenylalanine methylester) is a dipeptide artificial sweetener that is widely used as a non-nutritive sweetener in various food products [1]. The increased market of dietary products and the development of new synthetic sweetening compounds have not been sufficiently explored
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br Acknowledgements This work has been supported by TSTAR
2022-04-29

Acknowledgements This work has been supported by TSTAR USDA and Florida Citrus Advanced Technology Program Grants to D.B., C.P and R.S. One of us (D.B.) is an established scientist fellow at the Oak Ridge Institute for Science and Education (ORISE). This research was supported in part by an appoi
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