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herpes simplex virus 2 Analysis of the enzyme activity expre
2023-02-13
Analysis of the enzyme activity, expressed as rate of product formation per unit serum volume (20μl), between the diagnostic groups revealed that ApB activity was significantly decreased in the patient group both at recruitment and after 13months when the substrate concentration used was 1.5mM (pthe
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Based upon these findings the
2023-02-13
Based upon these findings, the 12S-lipoxygenase seems to increase membrane excitability by specifically inhibiting M-type K+ channels. The 12S-lipoxygenase is expressed in many parts of mammalian mma f australia including the cerebrum, cerebellum, hypothalamus, basal ganglia, hippocampus, olfactory
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Adiponectin also suppresses inflammatory stimuli induced NF
2023-02-13
Adiponectin also suppresses inflammatory stimuli-induced NF-kappaB activation, which may significantly contribute to the anti-diabetic and anti-atherogenic effects of adiponectin (Ouchi et al., 2000). The downstream mediators of AdipoR1 and AdipoR2, RPPAR and AMPK increase inflammatory responses by
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br Materials and Methods br Results br Discussion Voluminous
2023-02-13
Materials and Methods Results Discussion Voluminous literature is available describing the regulation of 2881 synthesis homeostasis by central and peripheral mechanisms in poultry [35,36]. However, the neuroendocrine mechanism(s) of photoperiod induced hypothalamic regulation of food intake
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Sodium Orthovanadate mg We have previously reported that int
2023-02-13
We have previously reported that interfering with Sodium Orthovanadate mg assembly dynamics by knocking down cofilin-1 in hMSCs increased polymerized actin that promoted osteoblast cell differentiation through a mechanism of enhancing focal adhesion kinase (FAK), p38 and c-Jun N-terminal kinase (JNK
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br Discussion Myopathic EMG changes are frequently detected
2023-02-13
Discussion Myopathic EMG changes are frequently detected in patients with MuSK MG, unlike in AChR MG patients [10]. However, these EMG changes are not always accompanied by myopathic histopathological findings. It has been shown that mitochondrial abnormalities seem to be more prominent in MuSK M
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An AXL decoy receptor with enhanced
2023-02-10
An AXL decoy receptor with enhanced GAS6-binding properties, MYD1, was engineered as a therapeutic tool to disrupt GAS6/AXL signaling in vivo (Kariolis et al., 2014). MYD1 was shown to block metastasis of human ovarian cancer (+)-Apogossypol and a murine breast cancer cell line in grafting assays in
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To maintain ATP levels postmortem muscle mobilizes its glyco
2023-02-10
To maintain ATP levels, postmortem muscle mobilizes its glycogen reserves to yield adenosine receptor agonist 6-phsphate that proceeds through glycolysis. Glycogen degradation was affected by the interaction between treatment and time (P of Na-azide (Pinitiation of the experiment. We expected that i
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br Experimental section br Acknowledgments br Introduction A
2023-02-10
Experimental section Acknowledgments Introduction Adipose is a major endocrine organ which releases a range of bioactive agents [1]. Selected adipose depots have been established as sites of sex steroid metabolism [1]. Subcutaneous and visceral adipose express high levels of aromatase, cap
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Aconitase clusters are prone to oxidations
2023-02-10
Aconitase clusters are prone to oxidations and are among the first to undergo a change in transition state during stages of electrophilic stress rendering them inactive [31]. Aconitase activity in LETO and OLETF did not differ at T0 suggesting that the early onset of insulin resistance may not be at
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The androgen receptor gene AR is located on
2023-02-10
The androgen receptor gene (AR) is located on the X-chromosome and consists of eight exons in humans (Brown et al., 1989; Kuiper et al., 1989). The similar gene structure in mice, monotremes and marsupials indicates AR is highly conserved in mammals (Choong et al., 1998; Faber et al., 1991; He et al
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Although several ARIs have reached various phases of clinica
2023-02-09
Although several ARIs have reached various phases of clinical experimentation however most of them have been withdrawn either due to an insufficient bioavailability, their poor efficacy or adverse side effects. Currently Epalrestat is in clinical use for the treatment of diabetic neuropathy. The si
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Although several ARIs have reached various phases of clinica
2023-02-09
Although several ARIs have reached various phases of clinical experimentation however most of them have been withdrawn either due to an insufficient bioavailability, their poor efficacy or adverse side effects. Currently Epalrestat is in clinical use for the treatment of diabetic neuropathy. The si
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Although several ARIs have reached various phases of clinica
2023-02-09
Although several ARIs have reached various phases of clinical experimentation however most of them have been withdrawn either due to an insufficient bioavailability, their poor efficacy or adverse side effects. Currently Epalrestat is in clinical use for the treatment of diabetic neuropathy. The sid
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Although several ARIs have reached various phases of clinica
2023-02-09
Although several ARIs have reached various phases of clinical experimentation however most of them have been withdrawn either due to an insufficient bioavailability, their poor efficacy or adverse side effects. Currently Epalrestat is in clinical use for the treatment of diabetic neuropathy. The sid
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